Bactrim is a drug that combines both sulfamethoxazole and trimethoprim antibiotics used to treat various types of bacterial infections. The generic label for Bactrim is sulfamethoxazole and trimethoprim.
Bactrim is supplied in two strengths which are 400mg sulfamethoxazole and 80mg trimethoprim for oral use. For DS “double strength”, the 2 dosage forms are 800mg sulfamethoxazole and 160mg trimethoprim. Aside from the two active ingredients, other inactive ingredients in Bactrim include sodium starch glycolate, pregelatinized starch, magnesium stearate, sodium benzoate 15% and docusate sodium 85%.
- Pharmacological Action
Bactrim brings together two medications sulfamethoxazole and trimethoprim, with each having a role to play in how this medication works. Sulfamethoxazole limits the release of dihydrofolic acid that is vital for human and bacterial metabolism. After sulfamethoxazole has completed its work, trimethoprim then inhibits the subsequent biochemical stage which is the discharge of tetrahydrofolic acid that is limited to microorganisms.
Bactrim is indicated for the treatment of a wide array of bacterial infections which include:
- Traveler’s diarrhea;
- Pneumocystis pneumonia;
- Otitis Media;
- Ear infections;
- Urinary tract infections;
- Prostatitis, and many other bacterial infections as directed by a doctor.
Bactrim cannot treat viral infections such as common colds or flu.
- Mode of Indication, Dosage, and Administration
Before you order Bactrim online or buy Bactrim for a local pharmacy, you must clearly follow the prescription guidelines as provided by your doctor. The recommended standard dosage for this drug is twice or thrice a day with or without food. Precise dosage, however, depends on the kind of infection and its severity. Tablets should be consumed with plenty of aqua to prevent kidney stones while on medication. For children, sulfamethoxazole and trimethoprim dosage is determined based on a child’s weight. Duration of treatment depends on the condition being treated and how a patient reacts to Bactrim. Do not skip a dose or stop taking medicine even if you feel better before completing your dose.
- Bactrim Side Effects
Typical side effects of Bactrim include:
- Loss of appetite;
- Fatigue and tiredness;
- Rash or mild itch;
- Ringing ears;
- Painful or swollen tongue.
Seek medical attention at once if you experience any of the following symptoms:
- Yellowing of the eyes and skin;
- Constant headache, weakness, and confusion;
- Slurred speech;
- Irregular heartbeat;
- Extreme dizziness and loss of balance;
- Severe diarrhea;
- Low blood cell count symptoms i.e. chills, fever, skin and mouth sores, pale skin, unusual bleeding, lightheadedness, and cold hands and feet;
- Mood changes;
- Blurred vision.
Before commencing Bactrim medication, you should inform the doctor or pharmacist medications you are currently using or if you experience any of the following conditions or reactions:
- Allergic to trimethoprim or sulfa medications;
- Kidney disease;
- Blood disorders such as anemia and porphyria;
- Severe allergic reactions;
- Underactive thyroid;
- Bone marrow suppression;
- Mineral imbalances i.e. high potassium levels or low sodium levels;
- Vitamin deficiency;
- Metabolic disorder i.e. G6PD deficiency;
- Expectant and breastfeeding mothers.
Bactrim may boost your sensitivity to sun exposure to reduce the time you spend outdoors in the sun.
- Drug Interaction
You should let the doctor know if you are on any of the following medications:
- Cyclosporine, leucovorin, amantadine, methotrexate, indomethacin, and pyrimethamine;
- Blood pressure medication such as quinapril, benazepril, enalapril, Ramipril, and Lisinopril;
- A diuretic or water pill such as hydrochlorothiazide and chlorthalidone.
Other drugs that may react with sulfamethoxazole and trimethoprim include over-the-counter drugs, prescription, herbal products, and vitamins.