What is Dapoxetine?
Dapoxetine is an antidepressant marketed as Priligy and Westoxetin used for treating premature ejaculation for men between the ages of 18 and 64 years. This drug is classified as an SSRI (Selective Serotonin Reuptake Inhibitor). Dapoxetine is known for its quick action which facilitates quick absorption and excretion from the body.
Each Priligy film-coated tablet has dapoxetine hydrochloride which is equivalent to 60mg or 30mg. Each 30mg tablet has 45.88mg of lactose while the 60mg tablet is comprised of 91.75mg of lactose.
Dapoxetine is an active ingredient in Priligy and is referred to as a short-acting selective serotine re-uptake inhibitor. The role of dapoxetine is to lower the activity of serotonin in the nervous system. Serotonin acts as a neurotransmitter that facilitates the movement of messages between nerve cells. One of the functions of serotonin is to transmit nerve messages that cause ejaculation. Dapoxetine monitors serotonin activity in the nervous system which assists in lengthening the time an individual takes to ejaculate and achieve better control over ejaculation.
Dapoxetine is indicated for the treatment of premature ejaculation for men aged between 18 to 64 years. Priligy tablets can only be prescribed after you’ve been carefully examined by a doctor and the medication is appropriate for use. Fortunately, you can purchase this drug from a walk-in pharmacy or online pharmacy, but only if you have a prescription from a doctor.
Mode of Indication, Dosage, and Administration
Priligy (dapoxetine) is available in both 30mg and 60mg tablets. Those on medication should only take one tablet approximately 1 to 3 hours before engaging in sex. The recommended dose, to begin with, is 30mg, but can always be increased to 60mg depending on the advice of your doctor. In most cases, an increase will only be recommended if the lower dose has failed to take effect and you’ve not had any side effects.
A tablet should be swallowed in its complete form with plenty of water and not chewed or crushed. You can take the medication with or without food. It is advised to take a full glass of water when taking the medicine to lower the effects if dizziness. You should only take a tablet if you are planning to have sex. Medication shouldn’t be taken more than once in a span of 24 hours. Dapoxetine should not be used as a daily regular medication as it’s intended for specific purposes. After treatment of 4-6 weeks, you may need to visit your doctor. One visit to a doctor every 6 months is recommended.
Dapoxetine Side Effects
Dapoxetine is associated with numerous effects which vary from one person to another. Chances are high men on this medication may experience one or two side effects. Symptoms of this drug are categorized into different categories. Common side effects of dapoxetine include:
- Feeling sick
Other side effects below may need to be monitored, if you feel bad, you may need to call a doctor.
- Feeling anxious, restless or agitated
- Excessive sweating
- Reduced sex drive
- Tingling sensation
- Sinus congestion
- Increased blood pressure
- Dry mouth
- Abdominal pain and discomfort
- Diarrhea and vomiting
- Indigestion and flatulence
- Difficulty to concentrate
- Ringing Ears
- Blurred vision
- Erectile dysfunction
- Feeling tired/sleepy
- Abnormal dreams/nightmares
- Mood changes i.e. nervousness and depression
- Dizziness or fainting
- Feeling disoriented or confused
- Slow or racing heartbeat
- Teeth grinding
- Feeling hot and weak
- Urgent need to empty bowels
Contraindication/ Who Shouldn’t Use Dapoxetine?
If you have any of the following conditions or you have suffered from it before. It is not advisable to use dapoxetine. Sharing this information with your doctor will ensure you remain safe during medication.
- Anyone below the age of 18 years
- History of fainting
- People with a history of heart problems i.e. heart valve symptoms and heart failure among others
- Individuals with epilepsy
- Bipolar affective disorder, severe depression, mania or hypomania
- People with severe liver or kidney problems
- Rare hereditary conditions such as Lapp lactase deficiency, glucose-galactose malabsorption, and galactose intolerance
- Low blood pressure or dizzy spells which your doctor might want to investigate further before prescribing dapoxetine medication
- Bleeding disorders such as hemophilia/ blood clotting
- Use of anticoagulants such as warfarin medication used to prevent blood clots
- Dehydration as a result of excessive vomiting or diarrhea. Chances of fainting are high when dapoxetine is consumed
- People with a risk of developing closed-angle glaucoma or raised pressure in the eyeball
Interaction with Other Drugs
Before taking dapoxetine medication, it is advisable to inform your doctor or pharmacist about details of any medication you are currently using, or have used recently. These should include all prescription, non-prescription, and herbal medicines. Also, don’t forget to check with your doctor or pharmacist before taking new drugs while still on Priligy treatment. Make sure all drug interactions with dapoxetine are safe before commencing medication.
Do not take dapoxetine (Priligy) with PDE5 medication (sildenafil, avanafil, vardenafil or tadalafil) that is used for erectile dysfunction treatment. Combining these drugs with dapoxetine can cause extreme dizziness and feeling like fainting.
Do not consume dapoxetine if you have taken any of the following medicines within the last two weeks. Additionally, you shouldn’t take any of these drugs until you have completed 7 days after your last dapoxetine medication.
- Monoamine oxidase inhibitor (MAOI) antidepressants i.e. moclobemide, phenelzine, tranylcypromine, and isocarboxazid
- SSRI antidepressants e.g. paroxetine, sertraline, fluoxetine
- Tricyclic antidepressants such as amitriptyline or clomipramine
- Triptans for migraine i.e. sumatriptan
Other medicines that you should stay away from as they could worsen the side effects of dapoxetine include: